Mortality is increased in people with AS and circulatory disease is the most frequent cause of death. People with AS have an increased risk of 60% for cerebrovascular mortality, and an overall increased risk of 50% for vascular mortality. About one third of those with ankylosing spondylitis have severe disease, which reduces life expectancy.
Ankylosing Spondylitis, Wikipedia
Author: Matt
Axial SpA pathogen-associated molecular patterns (2011 peer-reviewed)
Since IFN-Ξ² production is dramatically increased in response to pathogen-associated molecular patterns (PAMPs) via pattern recognition receptors (PRRs) [e.g. Toll-like receptors (TLRs)], we explored how the UPR influences IFN-Ξ² induction by reagents mimicking bacterial and viral infection.
From HLA-B27 to spondyloarthritis: a journey through the ER, 2011, Robert A. Colbert, Monica L. DeLay, and Erin I. Klenk
Hello
I suffer from Ankylosing Spondylitis (a form of Axial SpA). It is awful. I’ve started this blog/ActivityPub hybrid to raise awareness and share things I learn about my condition.
My name is Matt. You may know me from such hits as @lordmatt@mastodon.social and The Fantastic Site of Lord Matt. I am a geek, developer, and person often in pain. That last part, I rarely talk about.
I’m going to post occasional news along with quotes from papers I have read. I don’t plan to post all that often.
Please help me raise awareness of Axial SpA by following and encouraging others to follow. Each type of post is uniquely tagged if you want to filter them.